Preferential solvent interactions between proteins and polyethylene glycols.

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mechanism of Precipitation of Proteins by Polyethylene Glycols

The apparent solubilities of various proteins (14,000 to 670,000 daltons) were measured in the presence of polyethylene glycols (PEGS) of different sizes. All of the solubility curves, determined by measur ing the protein concentration in the supernate of centrifuged mixtures, exhibited the characteristic linear dependence of log S (g/liter) on PEG concentration (%, w/v). For human albumin in P...

متن کامل

Microbial degradation of polyethylene glycols.

Mono-, di-, tri-, and tetraethylene glycols and polyethylene glycols (PEG) with molecular weight up to 20,000 were degraded by soil microorganisms. A strain of Pseudomonas aeruginosa able to use a PEG of average molecular weight 20,000 was isolated from soil. Washed cells oxidized mono- and tetraethylene glycols, but O2 consumption was not detectable when such cells were incubated for short per...

متن کامل

Protein-solvent preferential interactions, protein hydration, and the modulation of biochemical reactions by solvent components.

Solvent additives (cosolvents, osmolytes) modulate biochemical reactions if, during the course of the reaction, there is a change in preferential interactions of solvent components with the reacting system. Preferential interactions can be expressed in terms of preferential binding of the cosolvent or its preferential exclusion (preferential hydration). The driving force is the perturbation by ...

متن کامل

Aerobic and anaerobic biodegradation of polyethylene glycols using sludge microbes

The aerobic and anaerobic biodegradation of polyethylene glycols (PEGs) in a model wastewater was investigated employing sludge microbes from Xiamen Terylene plant. The effect of molecular weight (MW) on the aerobic/anaerobic biodegradation of PEGs was assessed by performing shake flasks/sealed flasks experiments, respectively, using organic model wastewater containing PEG 600, 6000 and 20,000....

متن کامل

Mechanism of precipitation of proteins by polyethylene glycols. Analysis in terms of excluded volume.

The apparent solubilities of various proteins (14,000 to 670,000 daltons) were measured in the presence of polyethylene glycols (PEGs) of different sizes. All of the solubility curves, determined by measuring the protein concentration in the supernate of centrifuged mixtures, exhibited the characteristic linear dependence of log S (g/liter) on PEG concentration (%, w/v). For human albumin in PE...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1981

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)70019-2